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Tuberculosis (TB ) Signs And Symptoms World History Essay Help


Notifiable disease in the UK history assignment help book: history assignment help book

Notifiable disease in the UK. Why this and what process is involved

TB in the UK has increased because many people born in countries with high incidence, high homelessness, poor housing conditions and a high rate of people with substance/alcohol dependence.

TB is a notifiable disease, meaning clinicians must notify local authorities/public health England centre of suspected cases.

Medical practitioners are responsible for notifying the ‘proper officer’ at their local council of any suspected tuberculosis cases.

Immediately on the diagnosis of a suspected TB, Complete the notifications form. Don’t wait for laboratory confirmation of TB.

Then the clinician can send the form to the local authorities/public health of England within three days or notify them verbally within 24 hours if the case is urgent by phone, letter, and encrypted email or secure fax machine.

The local authority/public health must pass the entire notification to PHE within three days of a case being notified or within 24 hours for urgent issues.

Tests to confirm the active TB diagnosis history assignment help company

Tests to confirm the active TB diagnosis

Take detailed Complete patient history and examination and any information about recent travel. If there are signs and symptoms of TB, start treatment without waiting for culture results.

TB culture on samples: collect different respiratory samples, including a morning sample for TB microscopy and culture. This should begin before starting a treatment or within seven days of beginning treatment in severely ill people. Obtain other deep cough sputum samples; if that is impossible, use three gastric lavages or three sputum induction in children. Hospitalised patients may collect every 8 hrs. Send samples for TB culture from autopsy samples if pulmonary or laryngeal TB is suspected.


A chest X-ray is needed to evaluate a possible pattern association of pulmonary.TB may be found on any part, but the upper lobe is the most common.

In primary TB, the chest radiograph shows a pneumonia-like picture of the infiltrative process in the middle of lower regions.


CT scan of the chest help to better defines abnormalities in patients with vague abnormalities on chest radiography.


Nucleic acid amplification tests for M.tuberculosis complex include: the person has HIV, rapid information about mycobacterium species that would alter the persons care, the need for extensive contact tracing is being explored.


Blood cultures: using mycobacterium specific radioisotope labelled systems help to establish the diagnosis of active TB.


Latent TB test involves: world history essay help: world history essay help

Latent TB test involves and how the results are interpreted to confirm the diagnosis.

Potential contacts include the roommates, his family members who he went to visit.

Test: latent TB, which is tested using the Mantoux test.

For those with a latent TB infection, the skin will be sensitive (allergic)to PPD tuberculin, and a small, hard red bump will develop at the injection site, usually within 48 to 72 hours of having the test.

If there is no evidence of latent infection, the skin won’t react to the Mantoux test.

If the Mantoux test is positive, assess for active TB. If negative, offer treatment for latent TB infection. (regimens of isoniazid and rifampin or isoniazid plus rifapentine)

Offer interferon-gamma release assay if Mantoux test is unavailable.

Why tuberculosis is a complex condition apus history essay help

Why tuberculosis is a complex condition to treat regarding its cellular path physiology and the bacterial cell wall

In the pulmonary alveoli, the mycobacterium invades and replicate in alveolar macrophages, usually in the upper lobe of the lung generating a population of cells that grow at different rates, with different sizes and differ how they are susceptible to antibiotics. Mycobacterium is also transported to lymph nodes and via the bloodstream to other tissues and organs where secondary TB lesions can develop—the infection results in local granulomas and abnormal tissue destruction.

Mycobacterium can survive the host immune system and can cause lung damage and is transmitted through air, hence able to successfully infect a new host. It can take a long time to manifest, therefore making it difficult to treat.

Dormant cells even exist in patients with active disease, and these cells are less susceptible to antibiotics, and these make it difficult to interfere with the cell wall of infected cells

Mycobacterium has a waxy outer layer made of mycolic acids that makes them naturally impenetrable and difficult to penetrate with antibiotics